Baicalein High-purity Anti-inflammatory Anti-acne Stabilizing Raw Material(CAS 491-67-8)

Baicalein High-purity Anti-inflammatory Anti-acne Stabilizing Raw Material(CAS 491-67-8)

• Baicalein is a high-purity natural flavonoid active monomer refined from high-quality wild scutellaria baicalensis root raw materials via low-temperature ultrasonic extraction, high-precision membrane separation purification and freeze-drying technology.

• As a classic core anti-inflammatory and anti-acne flavonoid ingredient in the cosmetic industry, it has outstanding targeted anti-inflammatory, antibacterial and oil-regulating capabilities, far superior to ordinary plant soothing ingredients.

• Different from traditional anti-acne ingredients that are irritating, dry and easy to damage the skin barrier, and common soothing raw materials with weak anti-inflammatory efficacy, our cosmetic-grade 98% high-purity baicalein features pure natural plant source, ultra-mild and non-irritating, high activity and stable formula performance.

• It has multi-dimensional skincare advantages: firstly, it precisely inhibits the over-expression of inflammatory factors such as TNF-α, IL-6 and COX-2, blocks acne inflammatory cascade reaction from the source, quickly calms acne swelling, redness and heat sensation, and improves inflammatory acne problems; secondly, it has natural broad-spectrum antibacterial activity, inhibits the activity of acne-causing bacteria, regulates facial oil secretion, improves greasy pore blockage, and fundamentally reduces repeated acne breakouts; thirdly, it scavenges skin free radicals, resists oxidative damage caused by inflammatory stimulation, reduces post-acne dullness and inflammatory pigmentation, and accelerates skin repair; fourthly, it regulates skin microecological balance, reduces skin immune sensitivity, improves fragile oily sensitive skin, and realizes long-term skin stability without repeated inflammation.

• In addition, baicalein has excellent formula compatibility, can be perfectly compounded with quercetin, luteolin, naringenin, centella asiatica extract and panthenol to form a multi-effect flavonoid repair system, which greatly improves the formula's comprehensive efficacy of anti-inflammation, anti-acne and barrier stabilization.

• The product has stable physical and chemical properties, no discoloration or activity loss in conventional cosmetic processing, non-sensitizing, non-toxic and harmless, free of heavy metal residues, passed multiple skin safety tests, specially suitable for acne-prone skin and oily sensitive skin, and is a high-quality core raw material for mild anti-acne and inflammatory stabilization skincare products.

Key Benefits

• High-purity Flavonoid Monomer, Mild & Safe Anti-acne: 98% high-purity baicalein single flavonoid monomer, refined to remove invalid impurities. Pure natural scutellaria root extract, no chemical anti-acne agents, no irritation or dryness, safe for long-term use on acne-prone sensitive skin.

• Targeted Anti-inflammation, Rapidly Fade Acne Redness: Precisely acts on acne inflammatory pathways, inhibits inflammatory factor amplification, quickly relieves acne swelling, redness and heat, calms inflammatory skin lesions, and solves acute acne problems efficiently.

• Broad-spectrum Antibacterial, Inhibit Recurrent Acne: Natural antibacterial activity against acne-causing bacteria, improves pore blockage caused by oil accumulation, reduces acne recurrence, and regulates oily dull skin texture.

• Balance Oil Secretion, Purify Pore Environment: Mildly regulates sebaceous gland activity, controls excessive oil output, improves facial greasiness and shiny skin, refreshes skin texture, and keeps pores clean and breathable.

• Inhibit Post-inflammatory Pigmentation, Repair Acne Marks: Scavenges inflammatory free radicals, blocks post-acne dullness and pigment deposition, fades red acne marks, and restores clean and even skin tone.

• Excellent Compatibility & Industrial Stability: Good solubility and wide formula adaptability, can be freely compounded with various flavonoid and soothing ingredients to achieve synergistic efficacy amplification. Stable formula performance, no discoloration or precipitation during production and storage, suitable for industrial mass production.

Applications

• Acne Treatment Series: Mild anti-acne essence, inflammatory acne calming lotion, acne-soothing purifying cream, recurrent acne maintenance skincare.

• Oily Skin Purifying Series: Oil-control balancing essence, pore-refining lotion, greasy dullness repairing cream, daily oil-skin refreshing products.

• Oil-sensitive Skin Stabilizing Series: Oil-sensitive anti-redness essence, mild anti-inflammatory soothing lotion, fragile skin barrier repair cream.

• Post-acne Repair Series: Post-inflammatory pigment repair essence, acne mark fading lotion, acne skin delicate maintenance products.

• Functional Mask Series: Anti-acne purifying mask, inflammatory calming soothing mask, oil-control refreshing maintenance mask.

• High-end Custom Series: Compound flavonoid anti-acne skincare products, mild oil-skin stabilizing formulas, salon-level inflammatory repair raw materials.

Certificate Of Analysis (COA)

Frequently Asked Questions (FAQ)

• Q1: What is the core advantage of baicalein among flavonoid ingredients? 

A1: Baicalein is a rare flavonoid monomer with dominant anti-acne and targeted anti-inflammatory efficacy. Compared with quercetin, luteolin and other universal anti-inflammatory and antioxidant flavonoids, it has stronger antibacterial, oil-control and inflammatory calming capabilities, specifically targeting acne inflammation, oily blockage and recurrent acne problems, and is the core special raw material for acne-prone skin skincare.

• Q2: What is the recommended addition ratio of baicalein in skincare formulas? 

A2: Conventional anti-inflammatory maintenance products: 0.02%-0.1%; Mild oil-control purifying formulas: 0.05%-0.2%; Anti-acne inflammatory calming products: 0.1%-0.3%; Post-acne repair & anti-pigmentation formulas: 0.05%-0.2%; Mask essence formulas: 0.05%-0.15%. It is recommended to dissolve with ethanol first and add at low temperature (below 40℃) to ensure uniform dispersion and maximum activity retention.

• Q3: Will baicalein cause formula yellowing or color instability? 

A3: High-purity baicalein is natural fine yellow crystal powder with light color. After standardized ethanol-assisted dissolution and low-temperature feeding process, the formula is clear and stable. Strictly controlling the addition amount and avoiding long-term high-temperature and strong light environment will not cause obvious yellowing or precipitation delamination, which does not affect product appearance and shelf stability.

• Q4: What ingredients is baicalein suitable for compounding with? 

A4: Baicalein has excellent formula compatibility. It can be perfectly compounded with quercetin, luteolin, naringenin, centella asiatica extract, panthenol and beta-glucan to form a flavonoid synergistic anti-inflammatory and anti-acne system, which significantly improves the formula's oil control, anti-acne and barrier repair efficacy.

• Q5: How to store baicalein to maintain high activity? 

A5: Sealed, light-proof and low-temperature storage (2-8℃) is required. Avoid high temperature, strong light, humid environment and contact with strong oxidants to prevent activity attenuation and oxidation discoloration. Seal immediately after opening and use up within the validity period to ensure stable anti-inflammatory and anti-acne efficacy.

• Q6: Support trial order and professional technical guidance? 

A6: Yes, we support 100G small batch trial order to meet customer formula debugging and sample production needs. All batches have stable indicators and sufficient inventory. We provide professional pre-dissolution guidance, low-temperature feeding process suggestions and formula optimization technical support, supporting long-term bulk supply and global delivery.

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